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In addition, NAD + production by the NNT enhance SIRT3-mediated deacetylation and loss of NAD + -dependent deacetylase SIRT3 increases the acetylation of IDH2 at K413 and decreases its enzymatic activity by reducing dimerization, thus regulates mitochondrial redox status and promotes cell tumorigenesis in luminal B breast cancer, 137 and B cell malignancies
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Marshmallow root is included to provide nutritional support for gastrointestinal health, gut barrier function, and overall digestive wellness
Last updated: May 2026
Lee, S.-I
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