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Research using taste-masking compounds (cyclodextrins, ion-exchange resins) has shown modest reductions in perceived bitterness for some peptides, but the metallic aftertaste from arginine residues persists even in heavily flavored solutions

[1] Most of the time, those who are affected have no symptoms

274 , F111F119 (1998)

Partial hydrolysis will produce a mixture of shorter peptides and some amino acids

Overall, the data highlight the pharmacokinetic challenges of Schisandra chinensis lignans, such as poor solubility and extensive metabolism, necessitating advanced formulation strategies to optimize their therapeutic potential