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Image Credit: Anna Hoychuk/Shutterstock.com Ozempic functions primarily by enhancing insulin secretion, suppressing glucagon release, and reducing appetite, mechanisms distinctly tied to GLP-1 receptor activation
In consideration of the dual roles of GLP-1RAs in hypoglycemic effects and preventing CVD among T2DM patients, we reviewed the cardiovascular effects and molecular mechanisms of GLP-1RAs in CVOTs, animal models and cultured cells, and discuss how these findings transform pharmacotherapies for T2DM, and even expand the indication of this important category of anti-diabetic drugs to CVD patients without diabetes
Safety Considerations and Who Should Not Use GLP-1 Therapy Common side effects in non-diabetic users include nausea, vomiting, constipation, and diarrhea, typically mild to moderate and dose-dependent
They can also help provide additional support such as behavior change counseling and support groups that may be beneficial in helping you reach and maintain a healthier weight
Ho PY, Chou YC, Koh YC, Lin WS, Chen WJ, Tseng AL, Gung CL, Wei YS, Pan MH (2024) Lactobacillus rhamnosus 069 and Lactobacillus brevis 031: unraveling strain-specific pathways for modulating lipid metabolism and attenuating high-fat-diet-induced obesity in mice
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