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With an even higher hazard ratio than that of the type 2 diabetes group, the analysis again showed a higher risk of NAION for patients on semaglutide who were overweight or obese (hazard ratio: 7.64)
Under Canadas adult obesity guidelines, drug therapy is generally considered appropriate for adults with a BMI of 30 or higher, or 27 or higher with at least one weight-related condition (such as high blood pressure, type 2 diabetes, high cholesterol, or sleep apnea)
In the large-scale STEP clinical trials for semaglutide, diverticulitis was not identified as a common or high-risk adverse event compared to those taking a placebo
The additional acetyl group stabilises the S-acetylglutathione, allowing it to be better absorbed
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