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It is a surgical procedure that requires some form of anesthesia

IR leads to a decrease in the mtDNA copy number in mouse metaphase II (MII) oocytes, disordered mitochondrial distribution in germinal vesicle (GV) and MII oocytes, and abnormal mitochondrial inner membrane potential (increased in the GV stage and decreased in the MII stage), ultimately resulting in damage to mouse oocytes (Ou et al., 2012)

In such programs, the medication is shipped from a state-licensed pharmacy, and patients administer it themselves or with help from a trained individual

J Clin Biochem.Nutr