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tb 500

Unfortunately, in some cases, certain treatments can lead to even more complications

At 25M of menadione, there was a 13.3-fold increase for HEK-293 cells and 11.5-fold increase for K-562 cells in the amount of oxidized glutathione compared to the control

This is consistent with the known role of ARF6 as a negative regulator of ferroptosis in cancers such as pancreatic and gastric carcinoma (Geng and Wu, 2022)