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Compound Reference Data Compound: PT-141 CAS Number: 189691-06-3 Molecular Formula: C50H68N14O10 Molecular Weight: 1025.18 g/mol Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH Synonyms: Bremelanotide, Vyleesi, PT 141 Selected Published Studies The following peer-reviewed studies were conducted using animal models or in vitro cell-culture systems
GI events were most common (nausea, vomiting, decreased appetite)
This widespread microvascular starvation exacerbates the deep tissue fatigue, muscle pain, and cognitive impairments frequently reported by patients
Understanding these overlapping pathways is central to designing effective research protocols (2)
MHRA-approved options include orlistat (prescription and over the counter), semaglutide (Wegovy, supported by NICE TA875), and liraglutide (Saxenda, supported by NICE TA664)
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