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All insulins, including Toujeo, Lantus, Tresiba, Levemir, Humalog, and NovoLog, are insulin products, not GLP-1 medications

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The original weight management approval was based on the STEP (Semaglutide Treatment Effect in People with obesity) clinical trial program, which enrolled over 4,500 participants without diabetes

In receptor binding studies, it has been shown to have a GLP-1R and GLP-1 binding affinity, respectively, about five times lower than that of native and similar to endogenous GIP (40)

Delaying muscle wasting (sarcopenia)