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The overall pattern: topical GHK-Cu probably works for skin appearance with effect sizes that are real but modest
In the U.S., its not FDA-approved for general use, meaning its typically available through compounding pharmacies or research supply companies
Unlike many of the GLP-1 weight-loss drugs which are also synthetic peptides none of the seven peptides under consideration has undergone the kind of large-scale, rigorous trials in humans that are necessary for drug approval
Since selenate is typically found in waters, these authors also propose Se limits of 1 g/L in drinking water (while the EU and WHO regulations allow 2040 g/L) (49, 68)
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