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(Sodhi et al., JAMA 2023) Stay hydrated take frequent small sips of water or sugar-free squash throughout the day Temporarily switch to low-fibre foods: white bread, plain crackers, white rice, or pasta Eat small, frequent meals rather than large ones Avoid spicy, fatty, or very rich foods Ask your pharmacist about anti-diarrhoea medication let them know you are taking semaglutide See a doctor if it lasts more than 7 days, or if there is blood in your stools Constipation Because semaglutide slows down digestion, some people find that their bowels become sluggish

Encouraging patients to eat smaller, more frequent meals consisting of low fat foods rather than large ones consisting of extremely fatty foods can make a big difference

The modification involves substituting specific amino acids to enhance the stability and effectiveness of the peptide

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In 2023, more than a dozen peptides were placed in Category 2 effectively barred from compounding on the grounds of potential safety concerns