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Functional iron deficiency occurs under the following situations: Chronic lead poisoning : Lead inhibits the incorporation of iron into the porphyrin ring of heme via inhibiting heme sythetase, the enzyme that catalyzes this reaction in the last step of the heme synthesis pathway
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Sajith, M., Pawar, A., Bafna, V
Mar 2020;52(2):e13470
Internal changes during this phase include upregulation of collagen genes, increased growth factor production, and early accumulation of new extracellular matrix components
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