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Obeticholic acid, a clinical drug for non-alcoholic fatty liver disease treatment, can induce liver lipid peroxidation by affecting the gut microbiota, which subsequently mediates hepatocyte ferroptosis and compromises its antioxidative and antifibrotic effects [82]
(2002) in the Journal of Clinical Endocrinology and Metabolism
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NICE obesity guidance recommends evidence-based interventions including dietary change, physical activity, and licensed medications such as orlistat or semaglutide
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