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Further research has demonstrated that Amuc_1100 exhibits notable oxygen tolerance and functional stability within the complex intestinal microenvironment, with its antioxidant activity primarily mediated through the regulation of the NRF2 signaling pathway
153 Despite challenges such as compensatory upregulation of alternative transporters and feedback activation of resistance pathways, the transportome remains a tractable and druggable vulnerability
Lundgren JR, Janus C, Jensen SBK, Juhl CR, Olsen LM, Christensen RM, et al
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