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"Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model." Circulation

Bioconjugate Chem 26:22332242 VanBrunt MP, Shanebeck K, Caldwell Z, Johnson J, Thompson P, Martin T, Dong H, Li G, Xu H, DHooge F et al (2015) Genetically encoded azide containing amino acid in mammalian cells enables site-specific antibody-drug conjugates using click cycloaddition chemistry

The same principle applies: recalculate and adjust

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Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells