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Still, dont count this out entirely
They identified a distinct receptor, later named GHS-R1a, separate from the already-known GHRH receptor
Trapp S, Brierley DI (2022) Brain GLP-1 and the regulation of food intake: GLP-1 action in the brain and its implications for GLP-1 receptor agonists in obesity treatment
In this paper, the authors provide experimental evidence for the axon-protective benefits of remyelination and hence the likely therapeutic benefits of remyelination-enhancing treatments
This dual mechanism produces greater weight loss, and the addition of GIP signaling may have unique interactions with the metabolic state of ketosis that pure GLP-1 agonists do not
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