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Other melanocortin receptors like MC3R, MC4R, and MC5R exist, but MC1R is the main target related to skin pigmentation

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Although the difference between OA and HC serum was far less pronounced than FM and HC, limited to a single parameter, and FM serum had greater levels of anti-SGC antibodies than OA serum, it is possible that some individuals with OA have low levels of anti-SGC antibodies

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