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Table of Contents Toggle Glutathione and Its Role in the Body Glutathione is often referred to as the bodys master antioxidant for good reason

In macrophages, spermidine activates mitochondrial superoxideAMPKHIF-1 signaling and autophagy, down-modulates costimulatory molecules, and polarizes cells toward an M2-like phenotype, thereby dampening antitumor responses [148, 149]