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345 Other trials have shown omega-3 fatty acid supplementation can increase skin hydration, reduce skin itching, decrease depression symptom scores, and reduce levels of markers of oxidative stress and inflammation in CKD patients receiving hemodialysis

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Pollak 2008) has linked higher circulating IGF-1 to elevated risk of certain cancers in human cohorts

However, if it is demonstrated that TCF7L2 has some anti-inflammatory effects, GLP-1 receptor could be a crucial down-stream event for TCF7L2-mediated anti-inflammatory effects

PLoS One (2013) 8:e65763