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According to the Summary of Product Characteristics (SmPC), gastro-oesophageal reflux disease is listed as a common side effect, occurring in between 1% and 10% of patients

However, this approval was intended for adults with: A BMI 30 kg/m, or BMI 27 kg/m with at least one weight-related condition (e.g., hypertension, dyslipidemia, T2DM)

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Studies show that patients on semaglutide can lose 1522% of their body weight, but without resistance training and adequate protein, some of that loss includes lean muscle tissue

Rapid-acting insulin analogues (such as insulin aspart or insulin lispro ) before meals Insulin requirements change dramatically throughout pregnancy