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TARGETING MSTN IN METABOLIC DISORDERS: THERAPEUTIC POTENTIAL AND CLINICAL PROSPECTS As previously mentioned, higher serum MSTN levels have been observed in obese adults without other systemic diseases, and these individuals also exhibited reduced insulin sensitivity.[27] In addition, changes in the adiponectin levels, a key adipose-derived hormone that influences insulin sensitivity and glucose metabolism, have been reported to correlate with serum MSTN levels

You might eat a normal-sized meal and feel uncomfortably full

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Strength training 2-4 times per week, combined with adequate protein intake, preserves lean tissue and ensures the weight you lose comes primarily from fat stores