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The absence of an effect on psoriasis vulgaris suggests that SGLT2i may preferentially modulate joint-specific inflammation (enthesitis, synovitis) rather than skin inflammation, possibly through effects on entheseal resident cells or mechanical stress pathways
More specifically as patients lost weight there was a normalization of menses
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Lumps and bumps can be easily removed, and there is a very low risk of infection with modern types of filler like Juvederm
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