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Against retinoids: GHK-Cu in the Abdulghani trial outperformed tretinoin without the irritation, peeling, and sun sensitivity that retinoids commonly cause
doi:10.1074/jbc.M802030200
suggests that TB-500 may shape cell movement as it binds globular actin (G-actin) and may adjust how actin filaments assemble to plausibly render cells more capable of changing shape, migrating, and organizing into multicellular structures
The concentration achieved in tissues is higher with IV than any other method, which is why many experts consider IV the most effective route
A 7.5 mg dose at this concentration means injecting 1.5 mL, which is at the upper limit of what most people find comfortable for a subcutaneous injection
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