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While the exact experimental conditions (CCK concentration, incubation methods) differ in much of the literature, we directly tested conditions previously used to demonstrate that CCK peptide at 1 M enhanced GSIS in mouse islets and could not replicate those findings (Fig

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Despite the advances in technology and insulin delivery over the past several decades, less than a third of adults with type 1 diabetes in England and Wales achieve a target HbA 1c of 58 mmol/mol [7.5%] [8], and only 20% of patients in the US T1D Exchange Registry achieved HbA 1c 53 mmol/mol [7.0%] [9]

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In addition, mapping analysis of similarity between samples based on multivariate analysis using the analytical values of the detected sulfur-related compounds was performed using the R software package

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