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CMAJ Canadian Med Assoc J 172(9):11991209

Some state programs cover semaglutide and tirzepatide for weight management in patients with obesity, while others restrict coverage exclusively to patients with concurrent type 2 diabetes diagnosis

The overall cardiometabolic benefit of GLP-1RA rapidly expanded beyond the T2DM population, with the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT) trial describing MACE reduction in the population with overweight and obesity, even in the absence of T2DM [14]

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