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Differences In Nausea, Constipation, And Fatigue Rates While the side effect profile is similar overall, clinical trials have noted some subtle differences in the rates of specific symptoms
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Moreover, phenformin, at non-cytotoxic concentrations, had also an indirect anti-cancer effect through modulation of the chemokine milieu within the thyroid tumor microenvironment (inhibition of CXCL8 secretion) (Rotondi et al., 2018)
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