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evidence is still evolving
145 In the randomized trial, AE rates were higher in the CyA arm (94%) than in the PPS arm (56%), with three serious AEs in the CyA arm (increased blood pressure, increased serum creatinine) and one serious AE in the PPS arm (gross hematuria)
Findings in Beta-3-Adrenergic-Receptor Knockout Mice Another mouse study investigated the relationship between AOD9604 and beta-3-adrenergic-receptor biology
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That is a statistically significant difference, but the magnitude of weight loss is modest by any standard
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