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Proc Natl Acad Sci USA 109(17):65666571

In laboratory settings, researchers use GHK-Cu as a model compound to study tissue remodeling, extracellular matrix (ECM) regulation, copper handling, and redox (oxidation-reduction) signaling

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Ceramide generation was a critical component of Fas receptor-induced eryptosis, whereas therapy with natural organosulfur compounds inhibited the apoptotic death of erythrocytes by antagonizing oxidative stress and the Gardos channel that led to suppression of ceramide-initiated Fas aggregation in lipid rafts of these erythrocytes

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