why do glp 1 cause diarrhea Effects of GLP-1 receptor agonist on changes in the gut bacterium and the underlying mechanisms Why Ozempic Causes Diarrhea: GLP-1

Therefore it was posited to be the result of an increase in muscle tissues and water retention

Healthcare providers do not routinely measure circulating levels of GLP-1 medications because dosing is standardized based on clinical response (glycemic control, weight loss, tolerability) rather than blood concentrations

PMC4508379 Pickart, L., & Margolina, A

Clinical trials back this up: the STEP trials showed an average weight reduction of around 15% with Semaglutide, while the SURMOUNT trials reported up to 20% with Tirzepatide

And make sure GI side effects arent preventing them from getting the nutrition they need