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Patients with active cancer, uncontrolled diabetes, or pituitary disorders should not use growth hormone secretagogues without direct specialist oversight

Monitor interactions with other medications closely

Clinical Evidence: Semaglutide and Prediabetes Reversal The STEP and FLOW trials established that GLP-1 agonists reduce the risk of progression from prediabetes to type 2 diabetes by approximately 70% in patients with baseline fasting glucose between 110125 mg/dL

In: Howard R, Kullmann D, Werring D, Zandi M (eds) Neurology: A Queen Square Textbook, 3rd edn

GLP-1 drugs may cause more burping as a side effect due to slowed digestion