doi:10.1056/NEJMoa1109400
Initial concerns were raised after findings from the cardiovascular outcome trial (CVOT), Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes 6 (SUSTAIN 6), revealed a greater risk of DR-related complications, defined as the need for laser therapy, intravitreal injections, development of vitreous hemorrhage, and blindness, in semaglutide users compared to placebo (3.0% vs 1.8%, HR=1.76, P =.02)
In the last few years, these medications have become highly popular weight loss medications, which led to a national shortage of Ozempic and Wegovy in 2022
Does Aetna Cover Ozempic for Weight Loss
This is also the window where patients often begin to receive comments from people around them about looking different