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Lixisenatide Monotherapy GetGoal-Mono was a 12-week, double-blind, placebo-controlled trial that randomised 361 patients with type 2 diabetes of mean duration 1.11.4 years attempting to control their diabetes with diet and exercise alone, to lixisenatide OD for 12 weeks as a one-step dose increase (10 g for 2 weeks, then 20 g) or two-step dose increase (10 g for 1 week, 15 g for 1 week, then 20 g), or placebo also with a one- or two-step increase [17]

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