In its active form, the peptide binds divalent copper ions (Cu), with the histidine residue serving as the primary coordination site
In female rats, trauma led to reduced abundance of Bifidobacterium, Clostridium sensu stricto, Turicibacter , and Barnesiella genera some of which are involved in short-chain fatty acid (SCFA) production and serotonergic ( Turicibacter ) regulation (Laudani et al., 2023
Summary Side effects include tingling and decreases in taurine
doi: 10.3389/fphar.2025.1586231 Received 21 March 2025 Accepted 30 April 2025 Published 09 June 2025 Volume 16 - 2025 Edited by Irwin Rose Alencar de Menezes, Regional University of Cariri, Brazil Reviewed by Alaaeldin Ahmed Hamza, National Organization for Drug Control and Research (NODCAR), Egypt Mohannad A
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