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Overall, both the timing and dosage of circadian-modulating interventions are critical determinants of efficacy, with timing governing circadian alignment and dosage shaping the magnitude of metabolic and antioxidant responses

How stable is DSIP once reconstituted

Armed with the above data, which have recently come to light, we are now in a position to identify alterations possibly taking place in pathological pregnancies, ranging from tubal pregnancies to recurrent spontaneous abortions

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Here we review the components of the IGF-1 signaling pathway that are known targets of miRNA regulation, and highlight recent studies that suggest therapeutic potential of these miRNAs against various diseases