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The gastrointestinal tract contains rapidly dividing cells and a complex neural network
In high-fat diet (HFD) mouse models, subcutaneous dosing at approximately 0.3, 3, and 30 nmol/kg/day over 21 days produced dose-dependent body weight reductions
Jun 2019;124:35-38
By quieting glutamate signaling while enhancing GABA, DSIP creates conditions favorable for deep sleep without completely suppressing brain activity
Collectively, these results confirm that c-Myc is a key inhibitory mediator linking Gln deprivation to the regulation of miR-29b-3p expression
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