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The co-treatment of the cells with 3-PLG-ibu (100 g/ml) or 0.9 M ibuprofen (the estimated drug content of 3-PLG-ibu nanocarrier) did not change the toxicity of CK treatment after 24 h

Alpha-lipoic acid has been shown to lower several markers of inflammation

Downregulation of LAT1 ( SLC7A5 ) suppresses methionine input, thus reducing the level of cellular SAM, resulting in methylation depletion of some histones and inhibition of tumor growth

Subcutaneous injection addresses systemic regeneration while topical application provides localized skin support

Certificate of Analysis (COA) Applicable lots should be supported by batch-specific analytical documentation