do glp 1 make you thirsty On a GLP-1, dehydration can feel like absolute death and here's why 👇 1️⃣ Slower gastric emptying GLP-1s already slow digestion. Add dehydration and food + meds just sit there longer, which Why Your Water Intake Matters

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Higher NAD+ activates the sirtuin family of NAD+-dependent deacetylases, particularly SIRT1, which deacetylates PGC-1alpha (promoting mitochondrial biogenesis), FOXO transcription factors (enhancing stress resistance), and NF-kappaB (reducing inflammation)

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