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Overall, no significant change was observed in TMAO productivity after the carnitine intervention (TMAO AUC 574.70 vs
Contact your GP or diabetes specialist if you experience: Unexplained bone pain or persistent musculoskeletal discomfort Fractures from minor trauma (fragility fractures), which may indicate underlying bone weakness Significant unintentional weight loss of 5-10% over 3-6 months Difficulty maintaining adequate nutrition due to gastrointestinal side effects New or worsening symptoms suggesting calcium or vitamin D deficiency (muscle cramps, weakness, fatigue) Proactive discussion is particularly important if you: Are postmenopausal or over 65 years of age Have a personal or family history of osteoporosis or fragility fractures Take medications that affect bone health (corticosteroids, aromatase inhibitors, pioglitazone) Have medical conditions associated with bone loss Experience rapid weight loss that concerns you Have limited mobility or are unable to perform weight-bearing exercise Your GP can assess your individual fracture risk and determine whether investigations such as DXA scanning are appropriate
31 FatakhovaK.RahmanA.Al-NaqeebG.Al YassinS.AlqaisiS.RamdassA
Its a good idea to get this checked periodically to see how your treatment is affecting your heart health markers
Gilbert MP, Pratley RE
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