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This sudden release can lead to suboptimal drug concentrations at the intended target site in the body, diminishing the drugs therapeutic effect [339]
Sioutas GS, Mualem W, Reavey-Cantwell J, Rivet DJ 2nd
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That discrepancy is the core of the concern
QMP) in albumin reported to improve its pH-dependent binding to FcRn 11 , and found that this albumin engineering compensated for the decrease in receptor binding caused by L585 cleavage
