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He said it is clinician-led and evidence-based, and includes health monitoring and lifestyle changes
Randomized controlled trials have demonstrated that prophylactic intramuscular (IM) vitamin K injection of the newborn raises plasma vitamin K concentration, reduces PIVKA II (a marker of vitamin K deficiency), improves prothrombin time, and decreases the risk of classic VKDB compared to placebo (reviewed in 126 and 128)
Injection site reactions are most common
Combining them allows research into whether dual-pathway activation produces complementary or synergistic effects
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(PubMed) Jacobson EL, Shieh WM, Huang AC
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