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In addition to these physiological mechanisms, biopsychosocial factorssuch as the higher prevalence of central sensitization syndromes and mood disorders among patients with IBS, and particularly IBS-Mmay also contribute to the observed differences [28,29]

Sexual arousal: MC4R activation can induce spontaneous erections / increased libido in men [5]

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Ca 2 signatures, decoded by CaMs, CDPKs, and CBLs, emerge as key regulators of metabolic plasticity, linking nutrient sensing with hormonal and transcriptional responses