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Further experiments found that low-dose berberine can promote cell survival and antioxidant effects by up-regulating PI3K/AKT/Bcl-2 and Nrf2/HO-1 signal pathways
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Jiang M, Zhang X, Yan X, Mizutani S, Kashiwazaki H, Ni J, Wu Z (2021) GSK3 is involved in promoting Alzheimers disease pathologies following chronic systemic exposure to porphyromonas gingivalis lipopolysaccharide in amyloid precursor proteinNL-F/NL-F knock-in mice
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