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A systematic review found that GLP-1 receptor agonists significantly reduced albuminuria, a marker of kidney damage, and slowed the decline in kidney function, particularly in patients with early-stage renal disease
In December 2025 the US Food and Drug Administration approved the first oral GLP-1 for weight management, oral semaglutide sold as the Wegovy pill, and on 1 April 2026 it approved Lillys orforglipron, marketed as Foundayo, the first GLP-1 tablet that can be taken at any time of day without food or water restrictions
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19 Lenton KJ, San AT, Therriault H, Cantin AM, Payette H, Wagner JR
Whorwell, P
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