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421 By providing high-confidence protein conformations in the absence of experimental structures, AlphaFold enables a closed-loop pipeline in which generative AI supports rapid optimization from target modeling to oral candidate compounds, representing a new paradigm for AI-driven drug discovery targeting tumor immune resistance

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"GLP-1 receptor agonists in the treatment of type 2 diabetes state-of-the-art." Molecular Metabolism , 46, 101102