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Intravenous AOD-9604 Early human studies used single intravenous amounts of 25-400 mcg/kg

Oral glucose tolerance tests performed in clinical trials showed no significant changes in glucose handling, and fasting insulin levels remained stable throughout treatment periods

doi:10.1098/rsbm.2002.0011

[5] In a landmark 2014 study, knocking down NNMT in fat and liver protected mice against diet-induced obesity by increasing cellular energy expenditure, and raised adipose SAM and NAD levels

Any person with the signs or symptoms of a B12 deficiency should pay a visit to their doctor, but an injection may still provide them with benefits