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Existing spatial multi-omics integration methods typically assume that data of different modalities share a common latent distribution, aiming to project them into a unified low-dimensional space
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Of significance is the fact that the thiazolidinedione (TZD) class of drugs used to treat the hyperglycemia of type 2 diabetes (see the next section) activate PPAR which in turn increases the level of activity of PGC-1
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