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Clinical studies, including long-term trials (up to four years of oral supplementation), have found that ALA has a strong safety profile with no significant adverse effects at usual doses
Presented for research literature review only LoVecchio F et al
In a controlled trial involving healthy older women, twice-daily consumption of a protein beverage enriched with ~4 g of leucine elicited significantly greater increases in both acute and integrated myofibrillar protein synthesis compared with an isonitrogenous mixed-protein beverage containing lower leucine content
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Production happens in nearly every cell, especially in the liver , where detoxification demands are highest
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