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When semaglutide activates these receptors, it influences dopamine and serotonin pathwaysthe same systems targeted by many antidepressant medications
For those who weigh more, the target scales up to 1.5g per kilogram of body weight per day which works out to roughly 120g for someone weighing 180 lbs, 135g at 200 lbs, 153g at 225 lbs, and so on
In addition, these medications promote natriuresis
For residents and families navigating opioid addiction in the Seattle area
Dose escalation is guided by tolerability and your providers assessment of your response
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