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Its important to be aware of potential side effects while taking semaglutide, including nausea, diarrhea, vomiting, constipation, and abdominal pain
Despite the superior cardiorenal benefits of sodium/glucose cotransporter-2 inhibitors (SGLT-2i) and GLP-1RAs [75, 76], DPP-4i remained a common choice among these three classes of anti-diabetic agents, with more patients using DPP-4i than the other two [77]
Currently, both domestic and international studies have investigated the correlations between GLP-1RAs and medullary thyroid cancer, pancreatic cancer, colorectal cancer, prostate cancer, breast cancer, reproductive system tumors, and other oncological disorders
Its primary patents began expiring in 2024, making it the most accessible molecule for those looking to develop super-generics or fixed-dose combinations in the metabolic space
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