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For example, its involved in the synthesis of the inflammatory mediators leukotrienes and prostaglandins
As a representative molecule of NAMPs/DAMPs/PAMPs, the nuclear protein high-mobility group box protein 1 (HMGB1) plays an important role in CNS-related pathologies by being released from damaged cells 24
Hyperhomocysteinemia and Inflammatory Signaling Pathways in PD Inflammatory signaling pathways like nuclear factor kappa B (NF-B) and nod-like receptor pyrin 3 (NLRP3) inflammasome as well as other signaling pathways, are intricate in the pathogenesis of PD (Miller et al
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We further performed an expression microarray to determine the cause(s) of ibuprofen acyl-glucuronide-induced cytotoxicity
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