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The problem with lowering the dose of insulin in combination with having a SGLT-2 inhibitor on board is that the levels of ketones start to rise and push some people to DKA, a life-threatening complication, Mathieu said, adding that DKA primarily occurred in people who had a lower body weight, were on insulin pumps, or had a pump catheter obstruction

When to be concerned Certain effects warrant immediate attention: severe abdominal pain (potential pancreatitis indicator), significant changes in vision, signs of allergic reaction (swelling, difficulty breathing), or persistent vomiting that prevents hydration

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Meanwhile, some #telehealth providers such as #AgelessRx have launched early-stage trials of microdoses

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